Natural gums and resins usually possess low melting points and may be used hot or mixed with solvents. They usually have fair adhesion and excellent moisture resistance, but soften and loose strength at elevated temperatures.

Natural rubber compounds are used to bond linoleum or tiles to floors and acoustical material to ceilings. The rubber cements used for bonding paper, rubber, or leather are often made of natural rubber in a solvent but synthetic rubber is also used. Marine glues are often natural resins dissolved in a solvent that evaporates during hardening. Sealing wax is an example of a hot melt adhesive made of natural resins.